IGENOMIX (IVIOMICS in India) has shown that there is a 42% spontaneous miscarriage rate in women between aged between 38‐41 years when embryos with an unknown chromosomal status are transferred. This figure decreases to zero when chromosomally normal embryos previously analyzed by comprehensive chromosome screening (CCS) are transferred.
This is the main conclusion from the study “RCT study in advanced maternal age patients using array‐CGH: interim analysis”, presented in the latest European Society of Human Reproduction and Embryology 30th Annual meeting in Munich (Germany), from 29th June to 2nd July. This work analyzes the clinical value of the array‐CGH technique in women between 38‐41 years of age.
“Aneuploidy in human embryos increases with advancing maternal age. It is vitally important to analyze the embryos before their transfer in order to check if they carry any chromosomal abnormalities. This analysis allows the selection of euploid/normal embryos for the transfer, improving clinical outcomes and reducing the risk of miscarriage or and the birth of babies with chromosomal abnormalities”, explains Carmen Rubio, Head of PGD Molecular Cytogenetics at IGENOMIX.