ERA | Endometrial Receptivity Analysis Test | IVF Lab

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Overview

Many women undergoing IVF are unable to get pregnant, even after transferring good quality embryos. Although a good quality embryo it is an important starting point, it is also important to transfer the embryo into a uterus that is ready to receive the embryo.

The timing of embryo transfer must be in coordination with your body´s menstrual cycle, neither too early nor too late, just the right time. For most women, the best time to transfer an embryo is the same, but for some women, it can be different.

What is the endometrium?

The interior of the uterus is lined with a tissue called endometrium, which is prepared each month for the arrival of an embryo and it’s the nest where the embryo implants and resides during gestation. Even the best embryo will fail to implant if conditions aren’t right.

What is Endometrial receptivity?

The endometrium is receptive when it is ready for embryo implantation to occur. This period of receptivity is called the window of implantation.
Each woman has a unique window.knowing your personal window of implantation, you can optimize your chances of pregnancy doing a personalized embryo transfer.

What is ERA test?

ERA® is the first diagnostic test that determines each woman’s unique personalized embryo transfer timing, therefore synchronizing the embryo transfer with the individualized window of implantation.

*Simón et al. A 5-year Multicenter Randomized Controlled Trial of In Vitro Fertilization with Personalized Blastocyst Transfer versus Frozen or Fresh Transfer. Reproductive BioMedicine Online (2020). DOI:10.1016/j.rbmo.2020.06.002**Oral presentation, Clemente-Císcar, ESRHE 2018.

Why use ERA?

When performing the embryo transfer in a personalized way, the chances of getting pregnant are increased after the assisted reproduction treatment.
72.5%* pregnancy rate using ERA in the first IVF cycle in any patient.
Maximize your chances of pregnancy and don’t lose good embryos.
7 in 10 women gave birth after 1 year*.
Our recent randomized study* proves that a personalized embryo transfer is superior to the classic frozen embryo transfer.

Is ERA for you?

This test is recommended if:

Indicated for all patients starting assisted reproductive treatments, and has the greatest benefit for those who have experienced repeated implantation failures.

How does it work?

ERA test results

A RECEPTIVE RESULT

A receptive result shows that the window of implantation is located on the day of taking the sample. The recommendation is to proceed with embryo transfer under the same conditions as for biopsy.

A NON-RECEPTIVE RESULT

A non-receptive result shows a displaced window of implantation. In this case, with the ERA computational predictor, we will estimate your window of implantation indicating when your personalized embryo transfer is optimal in 90% of the cases. A second biopsy will be needed in only 10% of cases.