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Genetic Solutions > Emma

EMMA Endometrial Microbiome Metagenomic Analysis

The most comprehensive and precise panel, encompassing the most frequently detected and clinically relevant bacteria to evaluate the endometrium at the microbiological level

  • Technical Overview
  • Documentation
  • Scientific evidence
  • I’m not a health specialist

30%
of infertile women
have pathogenic bacteria detected in their endometrium

Upgraded EMMA panel:the most precise panel available, developed after analysing over 70,000 clinical samples during the last 5 years

The upgraded EMMA panel now identifies bacteria at the species level,
enabling more precise and targeted treatments

Are you interested?

Request information
Overview
  • Upgraded EMMA
  • Benefits
  • Indications

What is the EMMA – Endometrial Microbiome Metagenomic Analysis?

  • EMMA is a test that analyses the endometrial microbiome to help identify abnormalities associated with a poor reproductive prognosis.
  • EMMA assesses the endometrial microbiome, providing information about the most common and relevant bacteria, including those linked to higher pregnancy rates. EMMA also includes ALICE, which detects pathogenic bacteria that can cause chronic endometritis.
  • Igenomix has analysed over 70,000 clinical samples during the last 5 years.
  • Through our experience with the EMMA&ALICE tests, we have identified the bacterial pathogens most frequently detected in the endometrium.
  • Based on this data, we have developed the most comprehensive and precise panel, encompassing all clinically relevant bacteria, with most identified at the species level, enabling a more precise and targeted treatments.

What is the procedure?

Why use EMMA test?

  • EMMA uses RT-PCR technology to provide endometrial microbiome information by analysing the presence and quantity of the most common and relevant bacterial pathogens of the reproductive tract.
  • EMMA can also determine the abundance of Lactobacillus present in the endometrium; low proportions of Lactobacillus is associated with poor reproductive outcomes.
  • EMMA also includes ALICE, which detects pathogenic bacteria that can cause chronic endometritis.
  • EMMA determines whether the endometrial microbial environment is optimal or not for embryo implantation.
  • If the endometrial microbial environment is not optimal for embryo implantation, a recommendation for a precise and targeted treatment is provided.

Who should use the EMMA?

  • Patients with repeated implantation failure (RIF)
  • Patients with repeated pregnancy loss (RPL)
  • EMMA can be beneficial for any patient wishing to conceive, by assessing the microbiological environment that the embryo will encounter at implantation

*Moreno et al., 2016

Additional Information & Test limitations

  • These tests are not able to detect resistance to antibiotics
  • A negative result doesn’t rule out the presence of other endometrial pathogens
Documentation
  • EMMA Specialists' documents

Technical Sheets

Download

Brochure

Download

EndomeTrio Manual

Download
Scientific evidence

Relevant related studies:

Evidence that the endometrial microbiota has an effect on implantation success or failure. Moreno, Inmaculada et al. American Journal of Obstetrics & Gynecology, Volume 215, Issue 6, 684 – 703.

Download

Human Microbiome Project Consortium. Structure, function and diversity of the healthy human microbiome. Nature 2012; 486:207–14. 

Download


If you´re a little lost with this technical information...

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I’m not a health specialist

Igenomix and fertility

We work to make a world in which infertility is no longer an impossible barrier. Together with clinics and fertility specialists worldwide, we investigate human reproduction to change the lives of those who are trying to conceive.

Learn more about Igenomix

Other services you may be interested

ERA

Evaluates the endometrial receptivity

More information

EndomeTRIO

A new dimension of endometrial health

More information

ALICE

Detects the bacteria causing chronic endometritis

More information

Sex selection and Sex determination, before and after conception is prohibited and punishable under PC & PNDT act no. 57 of 1994

Igenomix is in the media

IGENOMIX has not affiliated any news outlet or publication identified above. News coverage does not constitute an endorsement of IGENOMIX or its products

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  • We guide you
    • Fertility
    • Inherited diseases
    • Worry-free pregnancy
  • Reproductive Health
    • Specialists
      • SAT
      • CGT
      • PGT-A
      • PGT-M
      • PGS+ERA Synchrony
      • Embrace
      • ERA
      • EMMA
      • ALICE
      • Endometrio
      • Family POC
    • Patients
      • SAT
      • CGT
      • PGT-A
      • PGT-M
      • PGS + ERA Synchrony
      • Embrace
      • ERA
      • EMMA
      • Family POC
      • ALICE
      • Endometrio
  • Diagnostic
  • About us
    • Igenomix Research
    • About Igenomix
  • ACADEMY
  • Language
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