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Synchrony by Igenomix

12 March, 2018

Synchrony by Igenomix

The success of IVF depends on a lot of factors such as the age of the woman, the quality of the embryo, status of the uterus etc. Often the IVF failures are a result of a poor quality embryo or the uterus not being ready for a transfer.

But the two major factors to consider for enhancing the chances of implantation during an IVF treatment are a chromosomally normal embryo and a receptive endometrium. If both the embryo and the endometrium are coordinated, the IVF clinician can transfer the right embryo at the right time.

Pre-implantation Genetic Screening (PGS) for Chromosomal Abnormalities

  • PGS enables selection of chromosomally normal embryos which have greater chances of resulting in a viable pregnancy
  • PGS uses the latest next generation sequencing (NGS) technology to screen the embryos for chromosomal abnormalities of all 24 chromosomes, hence increasing the chances of conception by 60% through IVF.
  • PGS with the added advantage of MitoScore enables to boost pregnancy rate by 70-80% by a single embryo transfer.

Endometrial Receptivity Analysis (ERA)

  • 1/3* of the chromosomally analyzed embryos do not implant. The lack of synchronization between the embryo ready to be implanted and endometrial receptivity is one of the causes of recurring implantation failure.
  • This genetic test identifies the patient’s Window of Implantation (WOI) to enable a personalized embryo transfer (pET).
  • It analyzes an expression of 236 genes involved in endometrial receptivity
  • Pregnancy rates above 85%** have been observed following indications of the ERA.

IGENOMIX presents a new solution, a new genetic technique “Synchrony”. This path-breaking new product brings the advantage of Endometrial Receptivity Analysis (ERA) and Preimplantation Genetic Screening (PGS) together to help IVF specialists achieve a successful pregnancy for their patients.